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Like all medical treatments, B12 injections may cause mild side effects in some individuals

For instance, topical applications often require higher concentrations at the site of action compared to injected methods, which bypass first-pass metabolism

Vitamin B12 is essential for the production of red blood cells, the maintenance of nerve cell function, and the normal metabolism of fats and carbohydrates

Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

It helps avoid going back to a deficiency

Vegetarians, people who've had weight loss surgery, and anyone taking medications for acid reflux or diabetes are also commonly affected