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Common indications include: Pernicious anaemia an autoimmune condition where the stomach cannot produce intrinsic factor, a protein necessary for B12 absorption [8] [9] Malabsorption disorders including Crohn's disease, coeliac disease, or following gastric surgery Strict vegan or vegetarian diets with confirmed deficiency though high-dose oral B12 may be sufficient if no malabsorption exists Certain medications such as metformin or proton pump inhibitors that may interfere with B12 absorption [9] [10] Neurological symptoms including peripheral neuropathy, memory problems, or balance difficulties related to deficiency Diagnosis should be confirmed through blood tests measuring serum B12 levels, full blood count, folate, and often anti-intrinsic factor antibodies

Immunol., 295, 1928 OptiPrepApplication Sheet C45

doi:10.1186/s12929-017-0390-4

Do maternal folate and homocysteine levels play a role in neurodevelopmental processes that increase risk for schizophrenia

The miR-29b-3p mimics and inhibitor were synthesized by GenePharma (China), and the relevant sequence information is provided in Supplementary Table S4

Nutritional/dietary supplements may be contaminated with banned substances not listed on the label