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This study explores a new source of immunogenic polypeptides originating from a nonconventional open reading frame within human insulin mRNA, which can be targeted by cytotoxic CD8 + T cells present in individuals with T1D, potentially contributing to -cell destruction in the disease

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Nutr Rep Internat 1984;29:1071-1079

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Signs and symptoms such as pupillary dilation, sweating, aberrant behavior, and dry mouth should be noted

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Lancet 371 , 16751684 (2008)

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on the other hand, it activates mitochondrial apoptosis via CHOP-dependent Bax/Bak translocation 50

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