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Consequently, integrating dietary modifications, such as CR, alongside preservation of ovarian somatic function represents a critical pathway for enhancing female health span and resisting oxidative stress [145, 147]

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It also seems to stabilize nitric oxide pathways, which are key to maintaining vascular health and controlling inflammation

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Conversely, the recent MOXI trial did not report a favorable effect of AOX treatment in infertile men in terms of improving clinical pregnancy, showing similar clinical pregnancy rates in both the treatment and placebo groups (9% in both groups, p=0.98) [42]