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Cardiovascular system Studies on acute and medium-term exposure to PET MNPs in mammals point to their potential detrimental effects on the cardiovascular system, mainly through induced oxidative stress, apoptosis, and changes in serum biochemical parameters

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These include orlistat, liraglutide, and semaglutide (NICE TA875 for weight management in adults with obesity), as well as GLP-1 receptor agonists within the framework of NICE NG28 (type 2 diabetes management)