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Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor
Deregulated expression of BAFF leads to autoimmune disorders in mice
the enzymes that reverse polyglutamylation
Shown to preserves β cell mass and restore glucose homeostasis
Less potent than Latrunculin A (Prod
Isthmin-1 (human) (rec.) (His) Pack Size:3 x 50 µg Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-knowIsthmin 1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain hind brain organizer called isthmus, with a proposed role during early brain development. Isthmin 1 encodes a predicted ~50 kDa protein containing a signal peptide, a thrombospondin domain and an adhesion associated domain. Isthmin 1 is important for embryonic and postnatal development. Growing evidence has shown that aberrant expression of Isthmin 1 can also affect the