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A continuous exposure might be necessary for chronic studies, whereas acute investigations might only require a single dose

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The product should not be given intravenously

Elevated intracellular cAMP levels activate protein kinase A (PKA), an enzyme that phosphorylates multiple target proteins

Evidence-Base Disclosure The published evidence base for AOD-9604 consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments

These observations are exploratory and not conclusive