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Overexpression of NOX4 inhibits mitochondrial respiration by reducing mitochondrial protein complexes, promoting mitochondrial ROS production, and thus inducing ferroptosis in astrocytes

The antioxidants also helps your heart stay youthful and strong, preventing the early onset of heart disease

Obstet Gynecol Surv 62:335347

Nirmalkar, K., et al

[9] These genes are believed to be involved in melatonin production and the circadian (day/night) control of hormone release

In practical terms, that shows up as fatigue that seems disproportionate to your effort, shortness of breath during workouts that used to feel manageable, and a general sense that your body isn't performing the way it should