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a GPCR that prevents or suppresses the secretion of insulin

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observed a marked increase in ACSL4 expression in a heart failure model induced by TAC in mice, and ACSL4 overexpression in cardiomyocytes exacerbates the cardiac dysfunction triggered by pressure overload through ferroptosis

However, male fertility parameters showed notable reductions, including decreased weight of the testis, epididymis, and seminal vesicle, as well as reduced sperm count and motility at doses of 300 and 600 mg/kg (700)