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Patients with MetSR demonstrated statistically significant improvement in depressive symptoms (DCD: SMD = 0.72, 95% CI: 1.41 to 0.03), while non-MetSR conditions showed no significant treatment effect (SMD = 0.57, 95% CI: 1.33 to 0.18)

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Clarke, G

Sanders, R

This may provide a model why so many more females have symptoms from toxic environments than males