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Participants also showed improvements in glycaemic control, cardiovascular risk markers, and physical function, adding to the drugs clinical profile beyond simple weight reduction

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Human evidence: Limited observational data in elderly patients showing fewer infections during treatment periods

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Beside a direct anti-inflammatory effect on infiltrating immune cells and resident glial cells, cortistatin may also avoid the infiltration of macrophages and neutrophils to the inflamed nerve by decreasing the release of a chemokine, such as CCL2, that is critically involved in the progression of neuropathic pain [59]

Symptom Relief : Potentially alleviates discomfort, bloating, cramping, and irregular bowel habits by promoting gut repair and reducing inflammation