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Apart from the well-documented GPx-like catalytic activity, ebselen is also reported for directly scavenging the biologically relevant ROS (like peroxyl and singlet oxygen) and reactive nitrogen species (peroxynitrite) with rate constants comparable to standard antioxidants

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In: Innovations in Modern Endocrine Surgery

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The autophagy inhibitor 3-methyladenine (3-MA) has been investigated as another means to inhibit iron accumulation and subsequent lipid peroxidation in irradiated human intestinal epithelial cells [44]