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Target the muscle or tissue under the skin

Relevant Research Ostarine and Ligandrol improve muscle tissue in an ovariectomized rat model Novel trifluoromethylated Ostarine (enobosarm) analogues with potent antiandrogenic activity and tissue selectivity in vitro in vivo YK-11 A Chemico-Biological Interactions study in rats found that 0.35 g/kg of YK-11 altered hippocampal neurochemistry, resulting in memory impairment (Dahleh et al., 2024)

Pros: Easier to measure smaller, more specific doses accurately