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(4) The researchers investigated cell culture models of fibrosis, which also expressed senescence markers such as more -galpositive cells and higher p16 and p21

In modeling, three templates such as 2F8A:A ( GPX1, GPX3, GPX6 , and GPX7 ), 2V1M:A ( GPX2 and GPX5 ), and 2P5Q:A ( GPX4 and GPX8 ) were used to maximize the alignment coverage, percentage identity and confidence for submitted sequences

Many of these areas are highlighted below in the figure adopted from Sen and Packer to illustrate these roles of glutathione and to emphasize the importance of maintaining the redox state of the cell[11]

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