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10.1038/cddis.2016.363 44 HuangL

A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices

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This functional loss may stem from age-related phagocytic exhaustion and the direct toxicity of iron-rich A and tau aggregates toward microglia (155) Furthermore, prior cell culture studies confirm that amyloid exposure accelerates microglial senescence (156)