CP-31398 restores DNA-binding activity to mutant p53 in vitro but does not affect p53 homologs p63 and p73
These reactions are the first two reactions in the pentose phosphate pathway, which provides an alternative to part of the pathway of glycolysis, yielding glyceraldehyde 3-phosphate and fructose 6-phosphate
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Carroll PV, Umpleby M, Alexander EL, Egel VA, Callison KV, Snksen PH, Russell-Jones DL