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The one compound that appeared to reduce bacterial burden did so because infected macrophages were washed away after 24-h treatment, rather than through bactericidal activity against intracellular bacteria

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Through the inhibition of phosphoinositide 3-kinase (PI3K), 3-MA disrupts the formation of autophagosomes, thereby impeding the initiation of the autophagic process

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Download PDF Info Publication number WO2019167070A1 WO2019167070A1 PCT/IN2019/050161 IN2019050161W WO2019167070A1 WO 2019167070 A1 WO2019167070 A1 WO 2019167070A1 IN 2019050161 W IN2019050161 W IN 2019050161W WO 2019167070 A1 WO2019167070 A1 WO 2019167070A1 Authority WO WIPO (PCT) Prior art keywords ghk hrs release transdermal transdermal composition Prior art date Legal status (The legal status is an assumption and is not a legal conclusion