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In animal models, visible effects typically appear after 4-6 weeks of consistent dosing, with long-term treatment producing weight loss and increased lipolytic sensitivity

When B12 levels are low, the body may struggle to metabolize these nutrients efficiently, leading to weight gain or difficulty losing weight

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Most labs use a normal range of 200-1200 ng/mL, but reversible symptoms of deficiency can be seen in patients whose blood levels fall within this range

Vitamin B12 deficiencies can be caused by many factors, such as older age, gastrointestinal conditions, and vegan or vegetarian diets