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Immunotherapy may be held and/or discontinued based on the type and grade of endocrine irAE

One study showed a daily dose of 2 grams of acetyl-L-carnitine caused nearly a 10-point reduction in systolic blood pressure, which is a key indicator of cardiovascular health and disease risk

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Despite ongoing efforts, most neuroprotectants have failed to demonstrate significant benefits in clinical trials, underscoring the need for novel mechanistic approaches

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