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Zinc-2-glycoprotein (ZAG) is a glycoprotein with a zinc-binding site that plays a pivotal role in lipid metabolism

Moreover, zinc suppresses Th17 cells by inhibiting glutaminolysis, which serves as the primary energy source for these cells, thereby lowering the risk of autoimmune diseases, such as autoimmune encephalomyelitis [333]

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A C18 fatty-diacid chain promotes reversible albumin binding and resistance to DPP-4 degradation, extending the plasma half-life to roughly 7 days and enabling a once-weekly dosing profile in research models

J Clin Endocrinol Metabol

Notably, they exhibit optimal stability in water and 10%FBS + DMEM, maintaining their integrity even after 17 h, which amply suffices for experimental purposes