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GLP-1R, widely distributed in the central nervous system, plays a crucial role in regulating various brain pathological processes, including neuroinflammation, nutrient metabolism, mitochondrial function, and synaptic function [50,51,52]

These pro-inflammatory hormones encourage this inflammation process and help your body heal the injured area

Clinical trials have confirmed its efficacy

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HIF-1 binds hypoxia response element (HRE) (Rashid et al., 2019) in promoter regions of target genes, influencing angiogenesis, cell proliferation, erythropoiesis, and cell metabolism (Hong et al., 2020), as well as a initiating inflammatory responses and compromising BBB integrity