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This peptide is considered a powerhouse due to its versatility across multiple systems, including musculoskeletal, gastrointestinal, neurological, and cardiovascular

Lockhart et al., 2023)

Therefore, therapeutic strategies that target the distinct mitochondrial metabolic features of CSCs and DTPs, such as disrupting the AMPKOXPHOS axis, inhibiting mitophagy, or decoupling metabolic signaling from DNA repair, represent a promising approach to overcoming chemoresistance in CRC

Beyond detoxification, GSH is essential for immune system function, DNA synthesis and repair, protein and enzyme activation, and the regeneration of other antioxidants such as vitamins C and E

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e071725e071725, www.bmj.com/content/383/bmj-2022-071725, Dangour, Alan D, et al