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Nevertheless, if such formulations can demonstrably enhance exposure two- to three-fold, reduce dosing frequency, or minimize adverse effects relative to standard therapy, they may ultimately prove cost-effective by lowering reliance on multiple drugs and reducing downstream healthcare costs

PMID: 97 CalventeCJTamedaMJohnsonCDDel PilarHLinYCAdronikouNet al

References PubMed Prakash & Goa (1999): Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency (pediatric GHD

Growth hormone (GH) has been shown to play a role in the onset of puberty, and it regulates the expression of steroidogenic acute regulatory protein (STAR) and steroidogenesis in progenitor Leydig cells (PLCs) [5]

Conventional methods like IV administration, liposomal delivery, and nasal sprays have proven ineffective for long-term optimization