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In very rare cases, they could have a severe allergic reaction called anaphylaxis

Sterility Meets USP 797 standards to ensure sterility and protection from microbial contamination

For additional safety information, please see Full Prescribing Information

The high dose of cyanocobalamin is generally well-tolerated due to the vitamins water-soluble nature and efficient excretion of excess amounts

Deviating from that schedule either skipping shots or getting too many can reduce effectiveness and increase the risk of side effects

however, these results were not excluded from corrections for multiple comparisons or the heat map generated with the data