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The divalent iron (Fe 2+ ) generated through intestinal absorption or degradation by red blood cells is oxidized to trivalent iron (Fe 3+ ), which becomes circulating iron by binding transferrin (TF) to form TF-Fe 3+ (Frazer and Anderson, 2014)

Astaxanthin: Astaxanthin is a powerful antioxidant known for its ability to protect skin cells from oxidative damage caused by free radicals

Therefore, both the levels and activity of IGF-IR are positively correlated with tumor progression

Journal of Clinical Pharmacy and Therapeutics, 26 (5), 363-367

chelating agents to sequester pro-oxidant metal ions

Protect them from direct sunlight and freezing temperatures