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Following interactions with biological molecules, ozone causes oxidative damage to all important biomolecules, including DNA, proteins, and lipids (Goldstein et al

Cessation of the offending agent leads to a regression in symptoms

Erler JT, et al

In particular, calycosin has been shown to induce p62 accumulation and Keap1 degradation, which facilitates the nuclear translocation of Nrf2

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A total number of 9,232 adults were available for gallstone disease history in NHANES 2017-March 2020 with 72 deaths with gallbladder or biliary tract disease