In line with this work, MET is enriched, during forebrain formation, in developing axon tracts and in the neuropil, mostly in pre- and post-synaptic compartments, mirroring an active transport to the synapse (Judson et al., 2009
Cortical neurons from G2019S- LRRK2 mice are more vulnerable to stress injury, and exposure to subtoxic doses of MPTP can cause severe motor dysfunction, selective loss of DA neurons, and increased astrocyte activation [101]
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