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Optimised bioavailability: liposomes act as a shell for glutathione and protect it from the acids and enzymes in the stomach and intestines

Typical doses range from 600 mg to 1,800 mg per day, depending on the condition being treated, and NAC should ideally be taken with food to avoid digestive upset

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150 mg/L AFB 1 (diluted in dimethyl sulfoxide), 2 mmol/L NADPH, 5 mmol/L GSH, rat cytosol, and recombinant GSTA2X (2.5 g total protein) were added at the same time

Some report a faint sulfur-like taste from the glutathione

Therefore, in IBD, in addition to providing in situ retention and sustained-release protection, it is also necessary to have certain oral stability, mucosal adhesion and inflammatory site targeting, so as to ensure the stability and local effective concentration of nanozym-hydrogel in the complex intestinal environment [145-147]