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Angiogenesis and anti-inflammatory/antioxidant signaling The preclinical literature also attributes to GHK-Cu the promotion of angiogenesis (the formation of new blood vessels, essential to feeding a healing wound), the recruitment of repair cells such as macrophages and capillary cells, and a set of anti-inflammatory and antioxidant effects

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In some embodiments, the otic formulation or composition comprises about 12% by weight of the povidone